Temperature tracking researched by IIT Madras

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IIT Madras researchers are improving temperature control based on ultrasound for treatment monitoring: Researchers from IIT Madras have developed ultrasound-based temperature control for non-invasive and compact treatment monitoring, which is better to use because there is no sensitivity to ionizing radiation and is ideal for point-of-care applications.

Ultrasound-based temperature tracking for treatment monitoring has been developed by the Indian Institute of Technology Madras Researchers. Ultrasound, unlike other imaging modalities, has many benefits, including protection (non-ionizing), real-time capability, and portability.

Temperature tracking for treatment researched by IIT Madras

The 'SITARE - Gandhian Young Technical Innovation (GYTI) Recognition 2020' for this project was awarded to the IIT Madras Research Team. This approach includes collecting diagnostic ultrasound signals from the tissue area of interest inside the body, where either microwave applicator or High-intensity Centered Ultrasound (HIFU) heating is applied non-invasively from outside, and analyzing these signals, primarily using prior knowledge of wave interaction physics with the tissue medium.

HIFU thermal therapy is now in use to treat solid tumors (both cancerous and benign). New state-of-the-art technology records MRI therapy (MR-guided HIFU). A typical clinical case for the treatment of uterine fibroids is Ultrasound-based tracking, instead of MRI, which would be the technology developed by IIT Madras Researchers, thus making it available and affordable.

Practical advantages in the healthcare sector of IIT Madras technologies include:

  • Non-invasive care and control of the process in real-time
  • Secure to use when no ionizing radiation contamination is involved.
  • Portable for point-of-care applications and suitable

Prof. Arun K. Thittai, Department of Applied Mechanics, IIT Madras, stressing the benefits of this technology relative to current technologies, said, "Having multi-parametric image input enables a wide variety of thermal therapies to be monitored in real-time accurately." Manufacturers will incorporate these techniques into current scanners as software and thus do not need any special electronic hardware.

The IIT Madras researchers have currently shown the viability of the techniques using studies performed on phantoms and ex-vivo tissue samples that resemble tissue. They are now working to convert these proof-of-concept techniques to design real-time imaging input based on an optimized microwave applicator cum ultrasound for potential clinical use. For the microwave applicator aspect, the research team includes faculty from the Engineering Design Department at IIT Madras. Researchers from the Department of Applied Mechanics, IIT Madras, have built a full in-house HIFU ablation setup.

While several ultrasound-based approaches have been suggested in the temperature monitoring literature, maps of changes in other properties at various temperature scales have not been exploited, mainly for HIFU-ablation. IIT Madras scientists have the benefit of getting access to the entire raw ultrasound data signal chain, and not just the final ultrasound image, which enables us to establish methods for monitoring several maps of different tissue parameters.

Where was the IIT Madras Ultrasound-based temperature monitoring performed for study in Care Monitoring?

This research was carried out at the IIT Madras biomedical ultrasound laboratory. Founded in 2014, it focuses on designing sophisticated, and inexpensive, imaging solutions for ultrasound imaging. In the last three years, more than half a dozen technology patents have been filed for ultrasound imaging techniques and equipment. A start-up was also spun off to create a proprietary technology ultrasound scanner that provides sophisticated and state-of-the-art functionality and is inexpensive.

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